Development of a Quality Measures Tool for the Use of Self-Injectable Biologic Therapy in Inflammatory Bowel Disease: An Integrated Specialty Pharmacy Initiative

This article discusses development of a quality measures tool to track outcomes for self-injectable biologic therapy used in the management of inflammatory bowel disease. Through a collaborative initiative, a set of clinical and specialty pharmacy quality measures was developed to assess outcomes such as patient safety, disease status, treatment efficacy, and healthcare resource utilization.
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Risk Factors for Non-Adherence to Biologic Therapy in Adult Patients with Inflammatory Bowel Disease (IBD)

The purpose of this study was to assess medication non-adherence [defined as medication possession ratio (MPR)]and validate the findings of risk factors for non-adherence to biologic therapy for adult inflammatory bowel disease: narcotic use, psychiatric diagnosis history, prior biologic use, and smoking. This study found that previously identified cumulative risk factors remain significant.
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Tofacitinib Adherence and Outcomes in Patients

This study retrospectively reviewed adherence and real-world outcomes of inflammatory bowel disease patients who initiated tofacitinib at a single care center. Sixty-three patients were identified. All patients failed at least on prior biologic therapy. Mean proportion of days covered was 95.7% for ulcerative colitis and 93.1% for Crohn's disease. Significant clinical and endoscopic response was seen. Adherence was high in a cohort with high refractory disease.
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Clinical Characteristics and Three-month Outcomes of Patients Prescribed Alternate-dose Self-injectable Biologic Therapy for the Management of Inflammatory Bowel Disease

This poster evaluates patient characteristics and 3-month outcomes in patients prescribed alternate-dose biologic therapy. Of 220 patients, one-third were previous/current smokers, and 40% had a psychiatric comorbidity. Median disease duration was 11 years (IQR 6-18), 46% previously underwent surgery.

HIV PrEP Access and Affordability: A Multidisciplinary Specialty Pharmacy Model

This study evaluated access and affordability of HIV PrEP in patients seen at a multidisciplinary PrEP clinic. In this cohort of mostly commercially insured men, the majority were able to access PrEP with low out-of-pocket costs facilitated by manufacturer assistance. Although generalizability beyond this population is limited, these results contradict perceived financial barriers to PrEP access.
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Healthcare Provider Attitudes and Knowledge Around Pre-Exposure Prophylaxis (PrEP) for the Prevention of HIV-Infection in Tennessee

In the Southern US, HIV prevalence is disproportionately high and PrEP use is disproportionately low. This cross-sectional survey study assessed Tennessee primary care providers’ current PrEP knowledge, attitudes, and prescribing practices with the aim to determine barriers to PrEP provision specific to TN providers.

Evaluation of Human Immunodeficiency Virus Curricular Content in Schools of Pharmacy in the United States

The purpose of this study was to explore student education about HIV and related topics using a cross-sectional, population-based survey of U.S. pharmacy schools with a 15-item questionnaire. We found diversity in the amount of time devoted to HIV didactic education among the 37 U.S. pharmacy schools who completed the survey, with some schools providing minimal didactic teaching on the topic of HIV along with low rates of exposure to PLWH in experiential training.
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Extended Adherence and Persistence to HIV PrEP in a Multidisciplinary PrEP Clinic

The obejctive of the poster is to describe PrEP medication adhernece and persistence in patients seens at a multidisciplinary PrEP clinic. Patients receiving PrEP in a multidisciplinary clinic with an integrated clinical pharmacist had high rates of adherence and persistene. Patients reported few side effects and reasons for discontinuation were appropriate.

Hepatitis C Treatment in HIV Coinfection: Approaches, Challenges, and Future Opportunities

While historical treatments combining interferon and ribavirin were less efficacious in HIV/HCV coinfection, modern direct-acting antiviral (DAA) therapies have shown similar clinical efficacy in HIV/HCV coinfection as in HCV monoinfection. In light of these findings, HIV/HCVcoinfected patients may benefit even more from new HCV treatment approaches. This article reviews the many therapeutic options for HIV/HCV coinfected patients with emphasis on avoiding drug-drug interactions.
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Real World Assessment of All-Oral, Sofosbuvir-Based, Hepatitis C Therapy at an Academic Medical Center with Integrated Specialty Pharmacy Services

This study was among the first to evaluate patient outcomes to all-oral, sofosbuvir (SOF)-based, HCV therapies in a real world setting and assess the impact of a clinic-integrated specialty pharmacy on therapy completion. We found higher completion rates in patients filling through VSP (97%) compared to outside pharmacies (93%), and a 100% medication access rate.