Efficacy and Safety of Abatacept, Adalimumab, and Etanercept in Pediatric Patients with Juvenile Idiopathic Arthritis

The objective of this study was to assess the efficacy of abatacept, adalimumab, and etanercept in pediatric JIA patients through changes in the Physician’s Global Assessment (PGA). We found that the majority of patients saw an improvement in their PGA score. Adverse events were similar across all three biologics, and the most common reason for biologic discontinuation was lack of response to therapy.
Download Publication

Evaluation of Response to Adalimumab Dose Intensification in Pediatric Patients with Inflammatory Bowel Disease

This study evaluated the response to adalimumab dose intensification (defined as a change in adalimumab therapy with reinduction or an increase in dosing frequency) in pediatric patients with inflammatory bowel disease.

Factors impacting teriparatide completion

In this study, we explored factors related to teriparatide completion. We found that patients utilizing VSP services were 62% more likely to complete teriparatide and 49% less likely to drop out of treatment after completing 12 months of teriparatide compared to non-VSP patients. Additionally, most patients (64%) required the use a financial assistance program only available to VSP patients. Smoking status also significantly impacted teriparatide completion.

Exploring Denosumab Therapy For Osteoporosis: Treatment lapses, discontinuations, and fracture incidence

In this study, we examined patients with osteoporosis prescribed denosumab. We explored the association between treatment lapses and discontinuations with fracture incidence. We also assessed reasons patients incurred a lapse in therapy or discontinued treatment, and discussed the role of the specialty pharmacist in supporting patient adherence and persistence.
Download Publication

Development of a Quality Measures Tool for the Utilization of Tyrosine Kinase Inhibitors in Non-small Cell Lung Cancer: An Integrated Specialty Pharmacy Initiative

The purpose of this initiative was to develop a tool to assess quality in the use of TKIs to manage NSCLC and ultimately track variables such as proper medication use, patient safety and healthcare resource utilization.
Download Development of Quality Measures Tool Publication

Specialty Pharmacist Management and Monitoring of Prescription Cannabidiol (AEs, DDIs, and interventions)

This study evaluated how specialty pharmacists manage prescription cannabidiol. Pharmacists play an integral role in medication access, resulting in a high approval rate and all patients being able to access therapy. Due to multiple drug interactions with prescription cannabidiol, pharmacists commonly changed the dose of interacting medications. Patient counseling and support for AE management was also a pharmacists key role found in this study.
Download Publication, DDI Mangement

Specialty pharmacy integration and the role of an advanced certified pharmacy technician in prescription cannabidiol access

The objective of this study was to measure time to medication access for prescription CBD from patient referral to first shipment when insurance approval process is managed by embedded specialty pharmacy team.Median time from initial assessment to first shipment was 7 days (IQR 4-13). Of patients for whom the CPhT helped obtain financial assistance (n = 14, 10%), all had $0 costs after assistance.
Download Publication

Specialty pharmacist integration into an outpatient neurology clinic improves pimavanserin access

In this study, we found the time to access pimavanserin reduced by 21 days on average after pharmacist integration. Similarly, the rate of third party approval increased by 16% and treatment initiation increased by 18%.
Download Publication

Persistence on Droxidopa for the Management of Orthostatic Hypotension at an Integrated Care Center

This was a single-center, retrospective analysis of persistence on droxidopa for the management of orthostatic hypotension in adults patients. This study also evaluated adherence, patient-reported adverse events and falls as well as healthcare resource utilization.
Download Publication

DMT Persistence, Switches, and Discontinuation in Patients with Relapsing Multiple Sclerosis

This study of patients with RMS and ≥3 fills of DMT from a health-system specialty pharmacy evaluated DMT persistence. The probability of remaining persistent for 3 years was 0.51. Non-persistent patients mostly switched to a new DMT (39%), discontinued the DMT (26%) discontinued, or transferred care to a new specialty pharmacy or provider (27%). Specialty pharmacists played a key role in DMT transitions and initiated 7% of DMT discontinuations and 36% of DMT switches.
Download Publication