Research Projects Page

Since our inception as an outcome committee in 2015, we have consistently and considerably expanded our ability to produce rigorous outcomes research. In 2018, we established a more formal program and leadership, including full time outcomes research staff. The result of these allocated resources has been a productive output across multiple specialty disease states. Below are highlighted outcomes from studies completed in recent years.

Research Project List

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61-70 of 140 results

Cost analysis of once daily extended-release tacrolimus (LCPT) and twice daily immediate-release tacrolimus (IR-Tac) for Kidney Transplant Patients

This study evaluated the out-of-pocket (OOP) costs of LCPT vs IR-Tac in kidney transplant patients, including the use of financial assistance, and found that at an institution with patient assistance grants, patients are less likely to have high out of pocket costs with LCPT compared to those prescribed IR-Tac.

Development and Implementations of a Laboratory Monitoring Dashboard to Reduce Therapy Gaps in Inflammatory Bowel Disease

The objective of this study was to evaluate the implementation of a dashboard to prevent therapy gaps by prospectively identifying patients on biologic therapy needing a new prescription with outdated labs. The new dashboard was highly effective at reducing the number of patients with a therapy gap, number of gap days, and days to receipt of a new prescription. Pharmacists and nurses reported high satisfaction rates with the new dashboard.

Management of Patients with Multiple Sclerosis within Health-System Specialty Pharmacies: A Multisite Analysis of Patient outcomes, Pharmacist Actions, Adherence, and Persistence

This multisite, prospective, cohort study of patients with MS evaluated patient-reported outcomes, pharmacists' actions, and DMT adherence/persistence. Patients reported low rates of impacted productivity, hospitalization, and relapse due to MS. Pharmacists commonly provided medication education and actions to ensure DMT safety and adherence. Patients had a high rate of adherence (median PDC 88%) and persistence (86% at 12 months). Findings support positive outcomes for HSSP patients.

Retraining of Transplant Pharmacy Staff to Reduce Medicare Part B Prescription Billing Errors in Post-Transplant Recipients

Because MedB billing error fines can be costly for pharmacies dispensing high-cost medications, identifying common errors and training staff can be useful and financially prudent. The aim of this quality improvement project was to retrain certified pharmacy technicians (CPhTs) on common monthly billing errors and evaluate changes in error rates and potential fines.

Implementation of a Standardized Specialty Pharmacist Documentation Tool Within the Electronic Health Record in an Integrated Outpatient Dermatology Clinic

We implemented a standardized documentation tool (SmartForms) that would collect discrete data fields during the specialty pharmacist's workflow in Dermatology clinic. This allowed us to collect data for reporting purposes on the front end, save time, document pharmacist interventions prior to treatment initiation, improve Epic documentation visibility and future usability.

Hepatitis C Cascade of Care in a Multidisciplinary Substance Use Bridge Clinic Model

The objective of this study was to characterize the HCV cascade of care in a bridge clinic setting and identify barriers to HCV treatment in this population. This study demonstrated that several challenges and barriers exist to engage patients in HCV care in a bridge clinic model, and more strategies should be identified to engage patients and link them to care.

Persistence on Droxidopa for the Management of Orthostatic Hypotension at an Integrated Care Center

This was a single-center, retrospective analysis of persistence on droxidopa for the management of orthostatic hypotension in adults patients. This study also evaluated adherence, patient-reported adverse events and falls as well as healthcare resource utilization.

Specialty Pharmacist Management and Monitoring of Prescription Cannabidiol (AEs, DDIs, and interventions)

This study evaluated how specialty pharmacists manage prescription cannabidiol. Pharmacists play an integral role in medication access, resulting in a high approval rate and all patients being able to access therapy. Due to multiple drug interactions with prescription cannabidiol, pharmacists commonly changed the dose of interacting medications. Patient counseling and support for AE management was also a pharmacists key role found in this study.

Harnessing the Electronic Health Record to Improve Workflow & Reporting in a Hepatitis C Clinic

This quality improvement project implemented the use of tools in the electronic health record that allowed specialty pharmacist to discretely document clinical data for Hepatitis C as part of their normal workflow. Post-implementation, the documentation burden for pharmacists was reduced and documented data was used to create a near real-time dashboard for reporting and tracking patient outcomes.

Assessing Patient-Reported Outcomes within an Inflammatory Bowel Disease Clinic at an Integrated Care Center

This study assessed patient-reported outcomes in patients prescribed specialty medications by an IBD clinic at a health system and dispensed by an integrated specialty pharmacy. A total of 515 MRQs were completed (median of 3 per patient; IQR 2, 3) during the study period. There were 2 reports of adverse effects and 11 reports of missing one or more medication doses. Medication effectiveness was rated as “excellent” in 13% (n=69) and “good” in 84% (n=433) of MRQ responses.